BAL (B-aggressive lymphoma) is a novel risk-related gene that is expressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) than in cured low-risk tumors. The major BAL cDNA encodes a 88 kDa nuclear protein. BAL-overexpressing B-cell lymphoma transfectants have significantly higher rates of migration than vector-only transfectants, indicating that the risk-related BAL gene promotes malignant B-cell migration.
Specificity
Reactivity has been confirmed in with human Farage non-Hodgkin′s B-cell lymphoma and human BC-1 B-lymphocyte lymphoma lysates.
Recognizes BAL.
Immunogen
Synthetic peptide derived from the C-terminal region of the short isoform of human BAL protein (B-aggressive lymphoma, poly (ADP-ribose) polymerase family member 9, PARP9).
Application
Anti-BAL Antibody is an antibody against BAL for use in IP & WB.
Research Category Apoptosis & Cancer
Epigenetics & Nuclear Function
Research Sub Category Tumor Markers
Transcription Factors
Western blotting: 1-3 μg/mL Immunoprecipitation: 7 μg/ reaction
Physical form
Format: Purified
ImmunoAffinity Purified
This polyclonal antibody is supplied in 400 μL of phosphate buffered saline (pH 7.4) containing 0.1% sodium azide.
Storage and Stability
Store at -20°C in undiluted aliquots for 1 year from date of shipment.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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