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AB10340

Sigma-Aldrich

Anti-ATP-binding cassette Antibody, sub-family B (MDR/TAP), member 1A

serum, Chemicon®

Synonym(s):

ATP binding cassette transporter 1, ATP-binding cassette 1, ATP-binding cassette transporter 1, ATP-binding cassette, sub-family A (ABC1), member 1, ATP-binding cassette, sub-family A member 1, ATP-binding cassette, sub-family A, member 1, Cholesterol ef

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse

species reactivity (predicted by homology)

rat

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

shipped in

wet ice

target post-translational modification

unmodified

General description

This protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. There are seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The MDR/TAP subfamily are involved in multidrug resistance. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes, and celiac disease.

Immunogen

Epitope: AA N629 – W704
Recombinant

Application

Anti-ATP-binding cassette, sub-family B (MDR/TAP), member 1A detects levels of ATP-binding cassette proteins & has been published & validated for use in WB.
Research Category
Metabolism
Research Sub Category
Toxicology & Drug Resistance
Western Blot Analysis: A 1:5000 dilution of this lot detected baculovirus expressed recombinant ABC protein.

Quality

Routinely evaluated by Western Blot on baculovirus expressed recombinant ABC protein.

Target description

141 kDa

Physical form

Raw rabbit serum with 0.05% sodium azide.

Storage and Stability

Maintain at -20°C for up to 12 months from date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1


Certificates of Analysis (COA)

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Adám Sike et al.
PloS one, 9(1), e84915-e84915 (2014-01-11)
The multidrug-resistant phenotype of tumor cells is acquired via an increased capability of drug efflux by ABC transporters and causes serious problems in cancer treatment. With the aim to uncover whether changes induced by epigenetic mechanisms in the expression level

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