8.52225

Fmoc-Met-OPfp

Novabiochem^®

• Synonym(s): Fmoc-Met-OPfp, N-α-Fmoc-L-methionine pentafluorophenyl ester
• Empirical Formula (Hill Notation): C₂₆H₂₀F₅NO₄S
• CAS Number: 86060-94-8
• Molecular Weight: 537.50
• MDL number: MFCD00065665
• UNSPSC Code: 12352209
• NACRES: NA.22

Properties

• Quality Level: 200
• product line: Novabiochem^®
• assay: ≥97.0% (HPLC)
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• mp: 130-140 °C
• application(s): peptide synthesis
• functional group: Fmoc
• storage temp.: 15-25°C
• InChI: 1S/C26H20F5NO4S/c1-37-11-10-18(25(33)36-24-22(30)20(28)19(27)21(29)23(24)31)32-26(34)35-12-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3,(H,32,34)/t18-/m0/s1
• InChI key: OKDPSRDTLNXPFQ-SFHVURJKSA-N

Description

General description

Pre-formed pentafluorophenyl ester for coupling of methionine amino-acid residues by Fmoc SPPS. Use enables bromophenol blue monitoring of amide bond formation.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Linkage

Replaces: 04-12-1512

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in chloroform): -14.5 - -11.5 °
DCU (DC (0004)): ≤ 2 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Solubility (0,5 mmole in 3 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315
• pcodes: P264 - P280 - P302 + P352 - P332 + P313 - P362 + P364
• Hazard Classifications: Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3