681670

Wogonin, S. baicalensis

A cell-permeable and orally available flavonoid that displays anti-inflammatory properties.

• Synonym(s): Wogonin, S. baicalensis, 5,7-Dihydroxy-8-methoxyflavone, WOG
• Empirical Formula (Hill Notation): C₁₆H₁₂O₅
• CAS Number: 632-85-9
• Molecular Weight: 284.26
• MDL number: MFCD00017736
• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: yellow
• solubility: DMSO: 10 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• InChI: 1S/C16H12O5/c1-20-15-12(19)7-10(17)14-11(18)8-13(21-16(14)15)9-5-3-2-4-6-9/h2-8,17,19H,1H3
• InChI key: XLTFNNCXVBYBSX-UHFFFAOYSA-N

Description

General description

A cell-permeable and orally available flavonoid that displays anti-inflammatory properties. Reported to suppress the release of NO by iNOS, PGE₂ by COX-2, proinflammatory cytokines, and MCP-1 gene expression and NF-κB activation.

Packaging

Packaged under inert gas

Warning

Toxicity: Irritant (B)

Other Notes

Lee, S.O., et al. 2006. Biochem. Biophys. Res. Comm.351, 118.
Kim, H.P., et al. 2004. J. Pharmacol. Sci.96, 229.
Chang, Y.L., et al. 2001. Mol. Pharmacol.60, 507.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable