66612-M

Urea

End product of the urea cycle. A topical keratolytic agent.

• Synonym(s): Carbimide, Carbonyl Diamide, Carbamide, Carbonyldiamide
• Linear Formula: NH₂CONH₂
• CAS Number: 57-13-6
• Molecular Weight: 60.06
• Beilstein/REAXYS Number: 635724
• MDL number: MFCD00008022
• UNSPSC Code: 12352111
• NACRES: NA.28

Properties

• Quality Level: 100
• assay: ≥98%
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated
• impurities: ≤0.01% insoluble material
• color: white
• mp: 132-135 °C (lit.)
• solubility: water: soluble
• density: 1.335 g/mL at 25 °C (lit.)
• cation traces: heavy metals: ≤0.001%
• storage temp.: 10-30°C
• SMILES string: NC(N)=O
• InChI: 1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
• InChI key: XSQUKJJJFZCRTK-UHFFFAOYSA-N

Description

General description

End product of the urea cycle. A topical keratolytic agent.

Application

Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

Warning

Toxicity: Irritant (B)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable