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516678-M

Sigma-Aldrich

4EBP1, His•Tag®, Human, Recombinant, S. frugiperda

4EBP1, His•Tag, Human, is a full-length, human recombinant 4EBP1 fused at the N-terminus to a His•Tag sequence and expressed in S. frugiperda insect cells.

Synonym(s):

PHAS-I, Human, Recombinant

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About This Item

UNSPSC Code:
12352203
Pricing and availability is not currently available.

recombinant

expressed in insect cells (S. frugiperda)

assay

≥75% (SDS-PAGE)

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

storage temp.

−70°C

General description

Full-length, recombinant, human 4EBP1 fused at the N-terminus to a His•Tag sequence and expressed in S. frugiperda insect cells. 4EBP1 negatively regulates translation and is inhibited by p70S6K phosphorylation. 4EBP1 is useful as a substrate in the study of p70S6K regulation and inhibitor screening.

Warning

Toxicity: Regulatory Review (Z)

Physical form

In 300 mM NaCl, 150 mM Imidazole, 50 mM Sodium Phosphate, 0.2 mM DTT, 0.1 mM PMSF, 25% Glycerol, pH 7.0.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Other Notes

Pause, A., et al. 1994. Nature.371,762.
Tsukiyama-Kohara, K., et al. 1996. Genomics.38,353.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 1


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