5.05481

MRS 2211 - Calbiochem

• Synonym(s): MRS 2211 - Calbiochem, 2-[(2-Chloro-5-nitrophenyl)azo]-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-4-pyridinecarboxaldehyde sodium salt, P2Y13 Purinergic Receptor Antagonist, MRS2211, MRS 2211, MRS-2211
• Empirical Formula (Hill Notation): C₁₄H₉ClN₄Na₃O₈P
• Molecular Weight: 496.64
• UNSPSC Code: 12352200
• PubChem Substance ID: 136068412

Properties

• assay: ≥95% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: dark red
• solubility: water: 70 mM
• storage temp.: −20°C
• SMILES string: CC1=C(C(=C(C(=N1)N=NC2=C(C=CC(=C2)[N+](=O)[O-])Cl)COP(=O)([O-])[O-])C=O)O.[Na+].[Na+]

Description

General description

A highly selective and competitive antagonist of P2Y13 purinergic receptor (pIC₅₀ = 5.97). Exhibits about 20-fold greater selectivity over P2Y1 and P2Y12 receptors.

Biochem/physiol Actions

Primary Target
P2Y13

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Kim, Y.C., et al. 2005. Biochem. Pharmacol.70, 266.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_c: Not applicable