489475

Anti-LRP-5/6 Mouse mAb (1A12)

liquid, clone 1A12, Calbiochem^®

• Synonym(s): Anti-Low Density Lipoprotein Receptor-Related Protein-5/6
• UNSPSC Code: 12352203

Properties

• biological source: mouse
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: 1A12, monoclonal
• form: liquid
• contains: ≤0.1% sodium azide as preservative
• species reactivity: mouse, human
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; avoid repeated freeze/thaw cycles
• isotype: IgG2b
• shipped in: wet ice
• storage temp.: −70°C
• Gene Information: human ... LRP5(4041)

Description

General description

Purified mouse monoclonal antibody. Recognizes the ~175 kDa full length LRP-5/6 and the ~145 kDa proteolytic fragment.

Recognizes the ~175 kDa full-length LRP-6 protein and a ~145 kDa proteolytic fragment.

This Anti-LRP-5/6 Mouse mAb (1A12) is validated for use in Immunoblotting for the detection of LRP-5/6.

Immunogen

Human

a synthetic peptide (DTGTDRIEVTR) corresponding to amino acids 421-431 of the human low density lipoprotein receptor-related protein 6 (LRP-6)

Application

Immunoblotting (1-2 µg/ml)

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In 150 mM NaCl, 10 mM Tris-glycine, 25% glycerol, 0.5% BSA, pH 7.0.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Other Notes

Li, L., et al. 2001. J. Biol. Chem.277, 5977.

Variables associated with assay conditions will dictate the proper working dilution.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable