420131-M

JNK Inhibitor III, Cell-Permeable, Negative Control

The JNK Inhibitor III, Cell-Permeable, Negative Control controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• Synonym(s): JNK Inhibitor III, Cell-Permeable, Negative Control, HIV-TAT₄₇₋₅₇-gaba-c-JUNδ₃₃₋₅₇, scrambled, Ac-YGRKKRRQRRR-gaba- DSNLIRGVLPTLMPKSLAQNKLKHA-NH₂, HIV-TAT₄₇₋₅₇-gaba-c-JUNδ₃₃₋₅₇, scrambled, Ac-YGRKKRRQRRR-gaba-DSNLIRGVLPTLMPKSLAQNKLKHA-NH₂
• Empirical Formula (Hill Notation): C₁₉₁H₃₃₆N₇₀O₄₈S
• Molecular Weight: 4413.22
• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• assay: ≥95% (HPLC)
• form: lyophilized solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic); protect from light
• color: white
• solubility: DMSO: 1 mg/mL
• storage temp.: −20°C

Description

General description

A cell-permeable 37 amino acid peptide that contains a scrambled sequence derived from the JNK binding domain (δ) of human c-Jun (amino acids 33-57) fused to the HIV-TAT transduction domain (amino acids 47-57) via a γ-aminobutyric acid (GABA) spacer. Does not disrupt c-Jun/JNK complex formation. Serves as a negative control for JNK Inhibitor III, Cell-Permeable (Cat. No. 420130).

A cell-permeable 37-mer peptide that contains a scrambled human c-Jun δ domain (amino acids 33-57) sequence linked to that of HIV-TAT protein transduction domain (amino acids 47-57) via a γ-aminobutyric acid (GABA) spacer. Does not disrupt c-Jun/JNK complex formation and thus serves as a negative control for JNK Inhibitor III, Cell-Permeable (Cat. No. 420130).

Biochem/physiol Actions

Primary Target
Serves as a negative control for JNK Inhibitor III, Cell-Permeable (Cat. No. 420130).

Warning

Toxicity: Standard Handling (A)

Sequence

Ac-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-gaba-Asp-Ser-Asn-Leu-Ile-Arg-Gly-Val-Leu-Pro-Thr-Leu-Met-Pro-Lys-Ser-Leu-Ala-Gln-Asn-Lys-Leu-Lys-His-Ala-NH₂

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable