250225

Cytochalasin B, Dihydro-

Induces changes in cell morphology and motility with no effect on sugar transport.

• Synonym(s): Cytochalasin B, Dihydro-
• Empirical Formula (Hill Notation): C₂₉H₃₉NO₅
• CAS Number: 39156-67-7
• Molecular Weight: 481.62
• MDL number: MFCD12910542
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (TLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: white
• solubility: methanol: 10 mg/mL; ethanol: 2 mg/mL; DMSO: 5 mg/mL
• shipped in: ambient
• storage temp.: −20°C
• InChI: 1S/C29H39NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14,18-19,22-24,26-27,31,33H,3,7,9-10,13,15-17H2,1-2H3,(H,30,34)/b14-8+/t18-,19-,22-,23+,24+,26+,27-,29-/m1/s1
• InChI key: WIULKAASLBZREV-RXPQEOCGSA-N

Description

General description

Induces changes in cell morphology and motility with no effect on sugar transport. Used as a specific marker in studies of high affinity cytochalasin binding sites unrelated to sugar transport. Disrupts the equilibrium between monomeric and polymeric actin.

Induces changes in cell morphology and motility with no effect on sugar transport. Used as specific marker in studies of high affinity cytochalasin binding sites unrelated to sugar transport. Disrupts the equilibrium between monomeric and polymeric actin.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Changes in cell morphology and motility

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)

Reconstitution

Following reconstitution refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Lin, D.C., and Lin, S. 1978. J. Biol. Chem.253, 1415.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H300 + H310 + H330,H351
• pcodes: P202 - P260 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Carc. 2
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable