A potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 3 µM).
Biochem/physiol Actions
Cell permeable: no
EC50 = 3 µM as PPARγ agonist
Primary Target Selective PPARγ agonist
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Harmful (C)
Reconstitution
Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Jha, R.J. 1999. Clin. Exp. Hypertens. 21, 157. Xin, X., et al. 1999. J. Biol. Chem. 274, 9116. Lohrke, B., et al. 1998. J. Endocrinol. 159, 429. Willson, T.M., et al. 1996. J. Med. Chem. 39, 665. Cantello, B.C., et al. 1994. J. Med. Chem. 37, 3977.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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