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Carcinoembryonic Antigen, Human Colon Adenocarcinoma Cell Line

Carcinoembryonic Antigen, Human Colon Adenocarcinoma Cell Line, is a native CEA from human colon adenocarcinoma cells.

Synonym(s):

CEA

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.42

Quality Level

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

aqueous buffer: soluble

shipped in

ambient

storage temp.

−20°C

General description

Native CEA from human colon adenocarcinoma cells. Found in tumors in adults. Presence indicates carcinogenic activity. Purified CEA has been the most widely-used general marker in determining and monitoring the status of malignant disease.
Native CEA from human colon adenocarcinoma cells. Found in tumors in adults. Widely used cancer marker found on many adult tumors. For more than a decade, purified CEA has been the most widely used general marker in determining and monitoring the status of malignant disease. This preparation is derived from an established adenocarcinoma cell line.

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Analysis Note

single diffuse band by SDS-PAGE

Other Notes

Nomoto, K., et al. 1998. Jpn. J. Cancer Res. 89, 1257.
Jacobs, E.L., and Haskell, C.M. 1991. Curr. Probl. Cancer15, 299.
Robertson, J.F., et al. 1991. Br. J. Cancer64, 757.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lincidio Perez et al.
Biotechnology and applied biochemistry, 43(Pt 1), 39-48 (2005-08-17)
In the present paper we report the development of a bivalent scFv (single-chain Fv) antibody fragment, starting from a mouse mAb (monoclonal antibody) specific for CEA (carcinoembryonic antigen) that has received approval for in vivo radioimmunodiagnosis in humans. The diabody
Ana Alvarez-Cienfuegos et al.
Scientific reports, 6, 28643-28643 (2016-06-28)
Here, we describe a new strategy that allows the rapid and efficient engineering of mono and multispecific trivalent antibodies. By fusing single-domain antibodies from camelid heavy-chain-only immunoglobulins (VHHs) to the N-terminus of a human collagen XVIII trimerization domain (TIE(XVIII)) we

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