219369
Carcinoembryonic Antigen, Human Colon Adenocarcinoma Cell Line
Carcinoembryonic Antigen, Human Colon Adenocarcinoma Cell Line, is a native CEA from human colon adenocarcinoma cells.
Synonym(s):
CEA
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About This Item
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Quality Level
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
aqueous buffer: soluble
shipped in
ambient
storage temp.
−20°C
General description
Native CEA from human colon adenocarcinoma cells. Found in tumors in adults. Presence indicates carcinogenic activity. Purified CEA has been the most widely-used general marker in determining and monitoring the status of malignant disease.
Native CEA from human colon adenocarcinoma cells. Found in tumors in adults. Widely used cancer marker found on many adult tumors. For more than a decade, purified CEA has been the most widely used general marker in determining and monitoring the status of malignant disease. This preparation is derived from an established adenocarcinoma cell line.
Warning
Toxicity: Standard Handling (A)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Analysis Note
single diffuse band by SDS-PAGE
Other Notes
Nomoto, K., et al. 1998. Jpn. J. Cancer Res. 89, 1257.
Jacobs, E.L., and Haskell, C.M. 1991. Curr. Probl. Cancer15, 299.
Robertson, J.F., et al. 1991. Br. J. Cancer64, 757.
Jacobs, E.L., and Haskell, C.M. 1991. Curr. Probl. Cancer15, 299.
Robertson, J.F., et al. 1991. Br. J. Cancer64, 757.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Biotechnology and applied biochemistry, 43(Pt 1), 39-48 (2005-08-17)
In the present paper we report the development of a bivalent scFv (single-chain Fv) antibody fragment, starting from a mouse mAb (monoclonal antibody) specific for CEA (carcinoembryonic antigen) that has received approval for in vivo radioimmunodiagnosis in humans. The diabody
Scientific reports, 6, 28643-28643 (2016-06-28)
Here, we describe a new strategy that allows the rapid and efficient engineering of mono and multispecific trivalent antibodies. By fusing single-domain antibodies from camelid heavy-chain-only immunoglobulins (VHHs) to the N-terminus of a human collagen XVIII trimerization domain (TIE(XVIII)) we
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