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Anti-phospho-EGFR (Tyr1173) Antibody, clone 9H2, Alexa Fluor™ 488

clone 9H2, Upstate®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

ALEXA FLUOR™ 488

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

9H2, monoclonal

species reactivity

mouse, human

packaging

antibody small pack of 25 μg

manufacturer/tradename

Upstate®

technique(s)

flow cytometry: suitable
immunocytochemistry: suitable

isotype

IgG1κ

NCBI accession no.

NM_005228.3
NM_201282.1
NM_201283.1
NM_201284.1

UniProt accession no.

P00533

shipped in

wet ice

target post-translational modification

phosphorylation (pTyr1173)

Gene Information

human ... EGFR(1956)
mouse ... Egfr(13649)

Specificity

the motif NAE[pY]LRV corresponding to the major autophosphorylation site of the human EGFR

Immunogen

KLH-conjugated, synthetic peptide containing the Y1173 motif (...NAE[pY1173]LRV...) of the human EGFR

Application

Anti-phospho-EGFR (Tyr1173) Antibody, clone 9H2, Alexa Fluor 488 detects level of phospho-EGFR (Tyr1173) & has been published & validated for use in FC & IC.
Research Category
Signaling
Research Sub Category
Growth Factors & Receptors

Quality

Routinely evaluated by positive immunostaining for phospho-EGFR in A431 cells.

Target description

175kDa

Storage and Stability

1 year at 4°C from date of shipment

Legal Information

ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Alexa Fluor™ is a registered trademark of Molecular Probes, Inc.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Intrinsic and acquired resistance to EGFR inhibitors in human cancer therapy.
Bianco, Roberto, et al.
Endocrine-Related Cancer, 12 Suppl 1, S159-S171 (2005)
Epidermal growth factor inhibition in solid tumours.
Ganti, Apar Kishor and Potti, Anil
Expert opinion on biological therapy, 5, 1165-1174 (2005)
Cetuximab.
Goldberg, Richard M
Nature Reviews. Drug Discovery, Suppl, S10-S11 (2005)
Structure and function of the epidermal growth factor (EGF/ErbB) family of receptors.
Leahy, Daniel J
Advances in Protein Chemistry, 68, 1-27 (2004)

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