16-235

Anti-phospho-erbB-2/HER-2 (Tyr1248) Antibody, Alexa Fluor^™ 488

Upstate^®, from rabbit

• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: ALEXA FLUOR^™ 488
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human, rat
• manufacturer/tradename: Upstate^®
• technique(s): flow cytometry: suitable; immunocytochemistry: suitable
• isotype: IgG
• NCBI accession no.: NM_001005862.1; NM_004448.2
• UniProt accession no.: P04626
• shipped in: wet ice
• target post-translational modification: phosphorylation (pTyr1248)

Description

Specificity

Predicted to cross react with rat based on conservation of immunogenic sequence

the activated form of Erb B2/HER-2 oncoprotein

Immunogen

Synthetic phosphopeptide, residues 1243-1255, corresponding to a major autophosphorylation (Tyr1248) site of human Erb B2/HER-2 (C-AENPEpYLGLDVPV)

Application

Research Category
Signaling

Research Sub Category
Growth Factors & Receptors

Kinases & Phosphatases

This Anti-phospho-erbB-2/HER-2 (Tyr1248) Antibody, Alexa Fluor 488 is validated for use in FC, IC for the detection of phospho-erbB-2/HER-2 (Tyr1248).

Quality

Routinely evaluated by immunostaining of EGF treated A431 cells

Target description

185kDa

Physical form

ImmunoAffinity Purified

Storage and Stability

1 year at 4°C from date of shipment

Analysis Note

Control
Negative Control: Catalog # 16-237, Normal Rabbit IgG, Alexa Fluor^™ 488-conjugate.

Legal Information

ALEXA FLUOR is a trademark of Life Technologies

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Alexa Fluor^™ is a registered trademark of Molecular Probes, Inc.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable