1.52023

Chromolith^® HighResolution RP-18 endcapped (monolithic) HPLC Columns

L × I.D.150 mm x 4.6 mm HPLC Column

• Synonym(s): Chromolith^® HighResolution RP-18 endcapped 150-4.6 HPLC column
• UNSPSC Code: 41115700
• NACRES: SB.52

Properties

• product name: Chromolith^® HighResolution RP-18 endcapped, L × I.D.150 mm x 4.6 mm HPLC column
• material: PEEK column
• Quality Level: 100
• agency: suitable for USP L1
• product line: Chromolith^®
• feature: endcapped; endcapped
• packaging: 1 ea of
• extent of labeling: 15% Carbon loading; 18% Carbon loading
• parameter: 200 bar pressure; 200 bar pressure; 45 °C max. temp.; 50 °C max. temp.
• technique(s): HPLC: suitable; HPLC: suitable; LC/MS: suitable; mass spectrometry (MS): suitable (High); mass spectrometry (MS): suitable (High)
• column L × I.D.: 15 cm × 4.6 mm
• surface area: 250 m²/g × 250 m²/g
• matrix: highly porous; monolithic silica; monolithic silica
• matrix active group: C18 bonding phase, octadecylsilane (ODS); C18 bonding phase
• pore size: 1.15 μm macroporosity; 1.5 μm macroporosity; 15 nm mesoporosity; 15 nm mesoporosity
• operating pH range: 2-7.5; 2-7.5
• separation technique: reversed phase
• storage temp.: no temp limit

Description

General description

Chromolith^® columns are made of monolithic silica with a characteristic bimodal pore structure.

Chromolith^® HighResolution RP-18 endcapped columns have macropores with 1.15 μm diameter, giving a column efficiency exceeding 140,000 plates/meter. The mesopores are 15 nm (150 Å), the surface modification is octadecylsilane with full end-capping.

Chromolith^® HighResolution RP-18 endcapped columns fall under the USP L1 Classification. The column efficiency is comparable to a 2.7 to 3 μm particle size fully porous particulate column. Chromolith^® HighResolution RP-18 endcapped columns are perfectly suitable for LC-MS applications.
The column dimension of 150 mm length and 4.6 mm I.D. is the best choice for high-resolution separations of complex compound mixtures on any HPLC System.

The revolutionary, monolithic silica with its unique combination of macropores and mesopores enables:
—Rapid separations at very low column back-pressure
—High matrix tolerance, allowing time and cost savings with simplified workflows
—Cost-savings due to extended column lifetimes
—Connection of columns, flow gradients and the use of mobile phases with higher viscosity

The recommended Guard-columns are:
Chromolith^® HighResolution RP-18 endcapped 5-4.6 guard cartridges (3 pieces) [1.52025]
with the Chromolith^® Guard Cartridge Holder 5 mm x 4.6 mm [1.52032]
The Chromolith^® column coupler can be used to significantly increase the separation efficiency of Chromolith^® columns by coupling several columns in series (up to 100,000 plates/per column). [1.51467]

Learn more:
Brochure: Race through your Separations on Any System. Chromolith^® Monolithic Silica HPLC Columns

All Supelco HPLC Columns, including monolithic Chromolith^® columns, are fully compatible to all HPLC and UHPLC Instruments.
Supelco HPLC Products: The Best Choice for Any LC Instrument

Chromolith^® HighResolution RP-18 endcapped columns are also available in 2 mm I.D. column dimension for perfect fit to UHPLC and UHPLC-MS needs.
Flyer: UHPLC-like performance - Rapid and Robust at Low Pressure - Chromolith^® HighResolution RP-18 endcapped 2 mm I.D. HPLC Columns

Legal Information

Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids