General description
Met M1268T is a somatic mutation that has been identified in patients with papillary renal carcinomas (HPRC). In vitro studies have demonstrated enhanced kinase activity from this mutant.
N-terminal 6His-tagged, recombinant, human, Met amino acids 974-end, containing the mutation M1268T.
expressed by baculovirus in Sf21 insect cells
Application
Active, N-terminal 6His-tagged, recombinant, human, Met amino acids 974-end, containing the mutation M1268T. For use in Kinase Assays.
Biochem/physiol Actions
- Protein Target: Met
- Target Sub-Family:TK
Packaging
Available in 250 μg --call for pricing and availability and reference catalog number 14-817M when ordering the 250 μg size.
Physical form
Format: Ni2+/NTA-agarose
Storage and Stability
6 months at -70°C
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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