119134

Adenosine 5′-O-(2-Thiodiphosphate), Trilithium Salt

A P₂-purinergic receptor agonist that acts as a potent insulin secretagogue.

• Synonym(s): Adenosine 5′-O-(2-Thiodiphosphate), Trilithium Salt, ADP-β-S, 3Li
• CAS Number: 73536-95-5
• MDL number: MFCD00077314
• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• assay: ≥80% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic)
• impurities: ≤10% ADP
• color: white
• solubility: water: 20 mg/mL
• shipped in: wet ice
• storage temp.: −20°C
• InChI: 1S/C10H15N5O9P2S/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(23-10)1-22-25(18,19)24-26(20,21)27/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H2,11,12,13)(H2,20,21,27)/t4-,6-,7-,10-/m1/s1
• InChI key: HCIKUKNAJRJFOW-KQYNXXCUSA-N

Description

General description

A P₂-purinergic receptor agonist that acts as a potent insulin secretagogue. Substrate and inhibitor of ADP-dependent enzyme systems.

Substrate and inhibitor of ADP-dependent enzyme systems. A P₂-purinergic agonist that acts as a potent insulin secretagogue.

Biochem/physiol Actions

Cell permeable: no

Primary Target
A P2-purinergic receptor agonist

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Shalev, M., et al. 1999. J. Urol. 161, 955.
Hillaire-Buys, D., et al. 1993. Br. J. Pharmacol. 109, 183.
Bertrand, G., et al. 1991. Br. J. Pharmacol.102, 627.
Eckstein, F., and Goody, R.S. 1976. Biochemistry15, 1685.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable