1.07735

Silica gel

beads, desiccant ~ 2 - 5 mm

• CAS Number: 112926-00-8
• MDL number: MFCD00011232
• UNSPSC Code: 41123003
• EC Index Number: 231-545-4
• NACRES: NB.21

Properties

• Quality Level: 200
• form: beads
• potency: >5000 mg/kg LD₅₀, skin (Rabbit)
• surface area: 700 m²/g
• loss: ≤2% loss on drying, 180°C
• particle size: 2-5 mm
• pore size: 2.0-2.5 nm
• pH: 5-8 (20 °C, 100 g/L in H₂O, slurry)
• bp: 2230 °C
• mp: >1600 °C
• bulk density: 750‑800 kg/m³
• storage temp.: no temp limit
• SMILES string: O=[Si]=O
• InChI: 1S/O2Si/c1-3-2
• InChI key: VYPSYNLAJGMNEJ-UHFFFAOYSA-N

Description

Application

• Chromatographic Applications: Silica gel is widely used as a stationary phase in chromatographic techniques for separating various chemical compounds. Innovations in silica gel modification, such as pentabromobenzyl group-modified silica gel, have enhanced the separation efficiency for metabolites like nicotinamide. This application is critical for pharmaceutical analysis and metabolomics studies, providing high precision and accuracy in quantifying biologically relevant molecules (Ozaki et al., Analytical Biochemistry, 2022).


• Environmental Pollutant Detection: Silica gel is employed in creating molecularly imprinted polymers (MIPs) that selectively recognize and bind environmental pollutants. A notable application involves embedding quantum dots in molecularly imprinted silica gel to detect aminoimidazo-azaarenes (AIAs) in food samples. This method offers high selectivity and sensitivity, making it a powerful tool for food safety and environmental monitoring (Qiao et al., Current Analytical Chemistry, 2021).


• Heavy Metal Removal from Water: Silica gel doped with specific reagents is used for the adsorption and removal of heavy metals from water samples. Recent research highlights the use of sol-gel silica doped with 3-(2-naphthoyl)-1,1-dibutylselenourea for the efficient removal of Pb(II) and Zn(II) from aqueous solutions. This application is essential for environmental remediation and ensuring water safety, showcasing the versatility and effectiveness of silica gel in addressing environmental pollutants (Mehmood et al., International Journal of Environmental Analytical Chemistry, 2022).

Analysis Note

Bulk density: about 75
Loss on drying (180 °C): ≤ 2 %
Water absorption capacity (24 hrs.,80 % relative humidity): ≥ 27 %

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable