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07-732

Sigma-Aldrich

Anti-HDAC6 Antibody, CT

Upstate®, from rabbit

Synonym(s):

Anti-CPBHM, Anti-HD6, Anti-JM21, Anti-PPP1R90

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_006044.2

UniProt accession no.

Q9UBN7

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... HDAC6(10013)

Specificity

HDAC6

Immunogen

6His-tagged fusion protein corresponding to residues 1031-1215 of human histone deacetylase 6 (HDAC6).

Application

Anti-HDAC6 Antibody, CT is a Rabbit Polyclonal Antibody for detection of HDAC6 also known as histone deacetylase 6 & has been tested in IP & WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones

Quality

Routinely evaluated by immunoblot.

Target description

134kDa

Linkage

Replaces: MABE546

Physical form

Format: Purified
Protein A purified

Storage and Stability

2 years at -20°C from date of shipment

Analysis Note

Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Homer2 deletion alters dendritic spine morphology but not alcohol-associated adaptations in GluN2B-containing N-methyl-D-aspartate receptors in the nucleus accumbens.
McGuier, NS; Padula, AE; Mulholland, PJ; Chandler, LJ
Frontiers in Pharmacology null
Withdrawal from chronic intermittent alcohol exposure increases dendritic spine density in the lateral orbitofrontal cortex of mice.
McGuier, NS; Padula, AE; Lopez, MF; Woodward, JJ; Mulholland, PJ
Alcohol null
Epigenetic status determines germ cell meiotic commitment in embryonic and postnatal mammalian gonads.
Wang, N; Tilly, JL
Cell Cycle null
Upregulation of miR-22 promotes osteogenic differentiation and inhibits adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells by repressing HDAC6 protein expression.
Huang, S; Wang, S; Bian, C; Yang, Z; Zhou, H; Zeng, Y; Li, H; Han, Q; Zhao, RC
Stem Cells and Development null
Xiaoran Wang et al.
Cell proliferation, 53(11), e12911-e12911 (2020-09-29)
Fibrotic cataract, including posterior capsule opacification (PCO) and anterior subcapsular cataract (ASC), renders millions of people visually impaired worldwide. However, the underlying mechanism remains poorly understood. Here, we report a miRNA-based regulatory pathway that controls pathological fibrosis of lens epithelium.
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