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V-017

Supelco

Nicotinic acid (Vitamin B3) solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

Nicotinic acid, Vitamin B3, 3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C6H5NO2
CAS Number:
59-67-6
Molecular Weight:
123.11
Beilstein/REAXYS Number:
109591
EC Number:
200-659-6
MDL number:
MFCD00006391
UNSPSC Code:
41116107
PubChem Substance ID:
329828960
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

236-239 °C (lit.)

density

0.791 g/cm3 at 20 °C

application(s)

clinical testing
clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

OC(=O)c1cccnc1

InChI

1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

InChI key

PVNIIMVLHYAWGP-UHFFFAOYSA-N

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General description

Nicotinic acid, also known as niacin, is a water-soluble vitamin of the B complex and essential human nutrient. Niacin deficiency, often the result of impaired nutritional status associated with conditions ranging from malnutrition to chronic alcoholism, is monitored in patient plasma samples by HPLC. This Certified Spiking Solution® is suitable for use as a starting material in the preparation of linearity standards, calibrators or controls in a variety of testing applications from diagnostic testing of niacin deficiency by HPLC to quality control testing of niacin-based pharmaceutical preparations, dietary supplements, or fortified foods.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

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Malte Lohölter et al.
Archives of animal nutrition, 67(3), 202-218 (2013-06-08)
The objective of this study was to investigate the effects of niacin and dietary concentrate proportion on body temperature, ruminal pH and milk production of dairy cows. In a 2 × 2 factorial design, 20 primiparous Holstein cows (179 ±
Ehab Haj Ali et al.
The West Virginia medical journal, 109(1), 12-14 (2013-02-19)
Niacin is an effective lipid-lowering agent which occasionally may cause hepatic failure. Liver enzymes are periodically tested during niacin therapy to assess for hepatic injury. We report a case of suppressed synthesis of hepatically derived coagulation factors and other liver
The use of complementary and alternative medicine for liver disease: part II.
Gerard E Mullin
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 28(2), 277-279 (2013-02-16)
Wanda C Lakey et al.
Journal of clinical lipidology, 7(2), 178-181 (2013-02-19)
Multiple cholesterol-reducing therapies have been shown to induce the regression of tendon xanthoma in patients with familial hypercholesterolemia. We present 3 cases of adverse reactions in Achilles tendon xanthomas after the addition of niacin and bile acid sequestrants to ongoing
Drugs for hypertriglyceridemia.
The Medical letter on drugs and therapeutics, 55(1411), 17-19 (2013-03-08)
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