Journal of environmental pathology and toxicology, 1(4), 377-395 (1978-03-01)
This overview provides a narrative survey of the reference literature on Kepone. The circumstances surrounding the "Hopewell incident" have increased the awareness and vigilance of state and federal agencies regarding human and environmental exposure to toxic chemicals. Highlights of this
Comparative toxicology of chlordecone (Kepone) in humans and experimental animals.
P S Guzelian
Annual review of pharmacology and toxicology, 22, 89-113 (1982-01-01)
Journal of toxicology and environmental health, 8(5-6), 743-755 (1981-11-01)
Chlordecone (Kepone) is a decachloroketone analog of the dodecachlorohydrocarbon mirex and is used as a stomach poison insecticide. Despite the structural similarity to mirex, chlordecone is unlike mirex in general organ-specific toxic properties. Chlordecone is primarily accumulated in the liver
Journal of environmental pathology and toxicology, 2(3), 671-686 (1979-01-01)
Kepone is unmistakably carcinogenic in rats and mice. Kepone induced malignant tumors in the liver of rats and mice in the NCI studies and in the liver in rats in the Medical College of Virginia study. Malignant tumors were also
Indian journal of biochemistry & biophysics, 30(4), 191-198 (1993-08-01)
Why is a low dose of toxic chemical nontoxic? What makes a larger dose of the same chemical toxic? Extensive work done to understand the mechanism of halomethane hepatotoxicity and its potentiation by chlorinated insecticide, chlordecone has resulted in the
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