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D-927

Supelco

Doxepin hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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1 ML
$28.20

About This Item

Empirical Formula (Hill Notation):
C19H22ClNO
CAS Number:
1229-29-4
Molecular Weight:
315.84
UNSPSC Code:
41116107
NACRES:
NA.24

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grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

CN(C)CC/C=C1C2=C(C=CC=C2)COC3=C/1C=CC=C3.[H]Cl

InChI

1S/C19H21NO.ClH/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19;/h3-6,8-12H,7,13-14H2,1-2H3;1H/b17-11-;

InChI key

MHNSPTUQQIYJOT-CULRIWENSA-N

Related Categories

General description

Doxepin is a tricyclic antidepressant used for the treatment of sleep maintenance and sold under trade names such as Silenor® and Aponal. This analytical reference standard is appropriate for use as starting material in calibrators or controls for numerous LC/MS or GC/MS applications such as forensic analysis, clinical toxicology, urine drug testing, or pharmaceutical research.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Silenor is a registered trademark of Somaxon Pharmaceuticals, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

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Yuliya Levintova et al.
International journal of pharmaceutics, 419(1-2), 96-106 (2011-08-02)
When liquid donors/receivers are used for in vitro skin permeation studies, excess hydration can change skin properties compared to in vivo conditions. A novel in vitro method of determining the permeability of drugs through skin was developed that avoids exposing
Yunes Panahi et al.
Skinmed, 9(3), 152-158 (2011-06-17)
Oral doxepin was shown to reduce chronic pruritus due to sulfur mustard. The present study compared the effects of topical doxepin 5% with betamethasone 1% for the treatment of pruritus in veterans exposed to sulfur mustard. This investigator-blinded, randomized, clinical
James L Zazzali et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 108(2), 98-102 (2012-02-01)
The literature on chronic idiopathic urticaria (CIU) lacks large-scale population-based studies. To characterize an insured population with CIU, including their demographic characteristics and comorbidities. We conducted a cross-sectional analysis using insurance claims. We included patients with 1 outpatient claim with
Donald R Lynch et al.
Cardiology journal, 19(4), 434-438 (2012-07-25)
Vorinostat is a histone deacetylase inhibitor used in the treatment of recurrent or persistent cases of cutaneous T-cell lymphoma (CTCL). A retrospective review of 116 patients from phase I and II clinical trials who had a baseline and at least
Xueqing Hu et al.
Neurochemistry international, 61(2), 207-218 (2012-05-09)
5-HT receptor changes remain controversial in posttraumatic stress disorder (PTSD) models. This study looks at the relationship between traumatic injuries and the alterations in 5-HT(2A) and 5-HT(2C) receptors in the goldfish brain. The effect of treatment with doxepin and fluoxetine
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