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A-071

Supelco

Alfentanil hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C21H33ClN6O3
CAS Number:
69049-06-5
Molecular Weight:
452.98
MDL number:
MFCD00941457
UNSPSC Code:
41116107
PubChem Substance ID:
329770623
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

CCN(N=N1)C(N1CCC2CCC(N(C3=CC=CC=C3)C(CC)=O)(COC)CC2)=O.Cl

InChI

1S/C21H32N6O3.ClH/c1-4-19(28)27(18-9-7-6-8-10-18)21(17-30-3)11-13-24(14-12-21)15-16-26-20(29)25(5-2)22-23-26;/h6-10H,4-5,11-17H2,1-3H3;1H

InChI key

AQORHZJDCHLLJN-UHFFFAOYSA-N

Gene Information

human ... OPRM1(4988)

General description

A Snap-N-Spike® Reference Solution suitable as starting material for use in calibrators or controls for a variety of LC/MS or GC/MS applications from forensic analysis and clinical toxicology to urine drug testing and pharmaceutical research. Alfentanil is a pharmaceutical synthetic opioid sold as Alfenta and Rapifen for pain relief and anesthesia.

Application


  • Highly sensitive electrochemical detection: Research has developed a promising electrochemical platform for detecting fentanyl and alfentanil in human serum, suggesting a highly sensitive method to monitor these potent analgesics in clinical settings (Li et al., 2023).

  • Pharmacodynamic analysis under anesthesia: A study compared the effects of electromyogram to bispectral index and 95% spectral edge frequency under remimazolam and propofol anesthesia, which could be relevant for alfentanil usage scenarios in surgical settings (Xin et al., 2023).

  • Opioid-sparing anesthesia: A propensity score matching cohort study demonstrated that dexmedetomidine provides stable hemodynamics and short hospital stays in non-intubated thoracoscopic surgery, applicable for integrating alfentanil as part of opioid-sparing strategies (Ke et al., 2023).

  • Response to opioid supply shortages: Discussion on potential responses to remifentanil supply shortages, highlighting alternative strategies including the use of alfentanil, offers insights into managing opioid resources in healthcare (Sneyd, 2022).

  • Vaccine development against synthetic opioids: A study on the preclinical efficacy and selectivity of vaccines targeting fentanyl, alfentanil, sufentanil, and acetylfentanyl suggests a novel approach to treating or preventing opioid abuse and overdose (Baehr et al., 2022).



Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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