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A-040

Supelco

Aminorex solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C9H10N2O
CAS Number:
Molecular Weight:
162.19
UNSPSC Code:
41116107

grade

certified reference material

form

liquid

feature

SNAP-N-SPIKE®. SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

SMILES string

NC1=NCC(O1)c2ccccc2

InChI

1S/C9H10N2O/c10-9-11-6-8(12-9)7-4-2-1-3-5-7/h1-5,8H,6H2,(H2,10,11)

InChI key

SYAKTDIEAPMBAL-UHFFFAOYSA-N

General description

An analytical reference standard suitable for use in LC/MS or GC/MS methods for clinical toxicology, forensic analysis, urine drug testing, or pharmaceutical research applications. Aminorex is an anorectic stimulant drug and appetite suppressant marketed under the names Menocil and Apiquel®. The drug was retired from the market after it was found to cause pulmonary hypertension.

Legal Information

Apiquel is a registered trademark of Puricorp Holdings LLC
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Relearning the lessons of history: anorexigens and pulmonary hypertension.
D Langleben
Chest, 114(1 Suppl), 55S-57S (1998-07-24)
M S Kramer et al.
Journal of clinical epidemiology, 51(4), 361-364 (1998-04-16)
In the late 1960s, an epidemic of primary pulmonary hypertension (PPH) occurred in Europe shortly after the introduction of aminorex fumarate, a potent anorexigen. A recently published case-control study from Europe reported that use of other anorexigens (the most prevalent
Lawrence R Soma et al.
American journal of veterinary research, 69(5), 675-681 (2008-05-02)
To investigate the pharmacokinetics and behavioral effects of aminorex administered IV and PO in horses. 7 Thoroughbreds. In a cross-over design, aminorex (0.03 mg/kg) was administered IV or PO. Plasma and urinary aminorex concentrations were determined via liquid chromatography- mass
M Humbert et al.
Clinics in chest medicine, 22(3), 459-475 (2001-10-10)
The present limitations in knowledge of the potential risk factors for PPH undoubtedly are attributable to the facts that PPH is a rare disease with an unknown pathogenesis and lacking large case series. Moreover, definite epidemiologic data are rare and
S A Barker
Journal of veterinary pharmacology and therapeutics, 32(2), 160-166 (2009-03-18)
Beginning in 2004, the horseracing industry experienced an epidemic of drug positives for the amphetamine-like drug aminorex. Investigation of the therapeutic treatment of the horses called positive for this drug suggested that its source was from the administration of the

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