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999986C

Avanti

4ME 16:0 Diether DG

Avanti Research™ - A Croda Brand 999986C

Synonym(s):

1,2-di-O-phytanyl-sn-glycerol

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About This Item

Empirical Formula (Hill Notation):
C43H88O3
CAS Number:
99341-19-2
Molecular Weight:
653.16
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 1 mL (999986C-5mg)
pkg of 1 × 2 mL (999986C-50mg)
pkg of 2 × 4 mL (999986C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 999986C

concentration

25 mg/mL (999986C-200mg)
25 mg/mL (999986C-50mg)
5 mg/mL (999986C-5mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](CO)(OCCC(C)CCCC(C)CCCC(C)CCCC(C)C)COCCC(C)CCCC(C)CCCC(C)CCCC(C)C

General description

4ME 16:0 Diether DG or 1,2-di-O-phytanyl-sn-glycerol is an archaeal lipid having two phytane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It is present as a component of the cell membrane in methanogen microorganisms.

Application

4ME 16:0 Diether DG or 1,2-di-O-phytanyl-sn-glycerol is suitable for use as an internal standard in:
  • the liquid chromatography mass spectrometric (LC–MS) analysis of lipids by multiple reaction monitoring (MRM) transitions
  • high performance liquid chromatography (HPLC) to quantify diacylglycerol (DAG/DG)
  • tandem mass spectrometric (MS/MS) analysisto quantify DAG

Biochem/physiol Actions

Ether linked lipids are antioxidant and essential for cell differentiation and cellular signaling.

Packaging

5 mL Clear Glass Sealed Ampule (999986C-200mg)
5 mL Clear Glass Sealed Ampule (999986C-50mg)
5 mL Clear Glass Sealed Ampule (999986C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A recent study revealed that the accumulation of gut microbiota-produced acetate (GMPA) led to insulin over-secretion and obesity symptom. To further develop this scientific point, the effect of resistant starch (RS) or exogenous acetate carried by RS (RSA) in the
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Sarabipour S, et al.
Biochimica et Biophysica Acta - Biomembranes, 1848(7), 1591-1598 (2015)
A new granulation method for compressed tablets [proceedings].
M H Rubinstein
The Journal of pharmacy and pharmacology, 28 Suppl, 67P-67P (1976-12-01)
S Görs et al.
Journal of dairy science, 99(11), 9313-9318 (2016-10-21)
Archaeol (1,2-di-O-phytanyl-sn-glycerol) is a cell membrane lipid component of methanogens that has the potential to be used as a biomarker for methane production in ruminants. However, its analysis via gas chromatography-mass spectrometry (GC-MS) is challenging because of its molecular size
Jinzhi Zhang et al.
Medical science monitor : international medical journal of experimental and clinical research, 23, 5345-5353 (2017-11-11)
BACKGROUND It is well known that, pathologically, Parkinson's disease is a common neurodegenerative disorder. In Parkinson's disease, the protein which is abundant in the human brain, alpha-synuclein, accumulates inside the nerve cells. In this situation, dysregulation of lipid metabolism performs
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