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880280C

Avanti

C16 PEG5000 Ceramide

Avanti Research™ - A Croda Brand 880280C

Synonym(s):

N-palmitoyl-sphingosine-1-{succinyl[methoxy(polyethylene glycol)5000]}

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About This Item

CAS Number:
212116-78-4
UNSPSC Code:
12352211

form

liquid

packaging

pkg of 1 × 2.5 mL (880280C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880280C

concentration

10 mg/mL (880280C-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)COC(CCC([(OCH2CH2)113OCH3])=O)=O

General description

C16 PEG5000 Ceramide is categorized as polymers & polymerizable lipids. Ceramides are prominent lipid molecules of stratum corneum. They belong to the group of sphingolipids.[1]

Application

C16 PEG5000 Ceramide might be used to stabilize nanosized bilayer disks[2] and in the preparation of lipid aggregates.[3]

Biochem/physiol Actions

Topical applications containing ceramides is known to repair and replenish the lipid levels in stratum corneum.[1]

Packaging

5 mL Clear Glass Sealed Ampule (880280C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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The design and development of anti-aging formulations
Skin Aging Handbook, 291-325 (2009)
Nanosized bilayer disks: attractive model membranes for drug partition studies
Johansson E, et al.
Biochimica et Biophysica Acta - Biomembranes, 1768(6), 1518-1525 (2007)
Melittin-Lipid interaction: A comparative study using liposomes, micelles and bilayerdisks
Lundquist A, et al.
Biochimica et Biophysica Acta - Biomembranes, 1778(10), 2210-2216 (2008)
Hudson P Pace et al.
Analytical chemistry, 90(21), 13065-13072 (2018-10-24)
Over the last two decades, supported lipid bilayers (SLBs) have been extensively used as model systems to study cell membrane structure and function. While SLBs have been traditionally produced from simple lipid mixtures, there has been a recent surge in

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