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880220C

Avanti

18:0 PEG5000 PE

Avanti Research™ - A Croda Brand 880220C

Synonym(s):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] (ammonium salt)

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About This Item

CAS Number:
474922-77-5
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 2.5 mL (880220C-25mg)
pkg of 1 × 20 mL (880220C-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880220C

concentration

10 mg/mL (880220C-25mg)
25 mg/mL (880220C-500mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC([(OCH2CH2)113OCH3])=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]

General description

18:0 PEG5000 PE, also known as 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] (DSPE- PEG 5000), is a mPEG phospholipid conjugate. It belongs to a class of polymerizable lipids.

Application

18:0 PEG5000 PE or 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] (DSPE-5K) has been used in the production of D−L microbubble.[1] It may also be used in preparation of liposomes for synthesis of light-activatable nanodroplets.[2]

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (880220C-500mg)
5 mL Clear Glass Sealed Ampule (880220C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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Saikat Das et al.
Langmuir : the ACS journal of surfaces and colloids, 36(13), 3573-3582 (2020-03-20)
Although several studies have demonstrated repetitive drug release using light-activatable liposomes, inconsistent drug release at each activation limits widespread usage. Here, we report reversible plasmonic material-coated encapsulated liposomes for proportional controlled delivery of methotrexate (MTX), which is a common drug
Richard J Browning et al.
Langmuir : the ACS journal of surfaces and colloids, 36(2), 609-617 (2019-12-20)
Microbubbles stabilized by an outer lipid shell have been studied extensively for both diagnostic and therapeutic applications. The shell composition can significantly influence microbubble behavior, but performing quantitative measurements of shell properties is challenging. The aim of this study is

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