870436P
Avanti
C16:0 anandamide phosphate
Avanti Research™ - A Croda Brand 870436P, powder
Synonym(s):
palmitoyl ethanolamide phosphate (sodium salt)
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About This Item
Empirical Formula (Hill Notation):
C18H37NO5PNa
Molecular Weight:
401.45
UNSPSC Code:
12352211
NACRES:
NA.25
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form
powder
packaging
pkg of 1 × 1 mg (870436P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 870436P
shipped in
dry ice
Storage temp.
−20°C
SMILES string
O=C(CCCCCCCCCCCCCCC)NCCOP(O)([O-])=O.[Na+]
General description
C16:0 anandamide is fatty acid amide, endogenic in nature. It is a member of the N-acylethanolamines family. Palmitoyl ethanolamide is present in egg yolk and peanut.
C16:0 anandamide phosphate is a phosphate ester of C16:0 anandamide. C16:0 anandamide, also known as N-palmitoyl ethanolamide, is a N-acyl ethanolamide derivative of palmitic acid.
Biochem/physiol Actions
Anandamide is a ligand for cannabinoid receptors. Anandamide possesses anti-inflammatory and pain killing action. It is effective in relieving pain associated with nerve compression syndrome and pudendal neuralgia. Anandamide is also useful in treating atopic eczema. Its effect is mediated by cannabinoid CB1 and CB2 receptors.
C16:0 anandamide or palmitoyl ethanolamide exhibits anti-inflammatory and analgesic properties. It is currently used as a veterinary anti-inflammatory agent.
Packaging
5 mL Amber Glass Screw Cap Vial (870436P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
flash_point_f
No data available
flash_point_c
No data available
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Palmitoylethanolamide ameliorates carbon tetrachloride-induced liver fibrosis in rats
Ohara M, et al.
Frontiers in Pharmacology, 9, 698-711 (2018)
Ocular hypotensive effect of oral palmitoyl-ethanolamide: a clinical trial
Gagliano C, et al.
Investigative Ophthalmology & Visual Science, 52(9), 6096-6100 (2011)
Protective role of palmitoylethanolamide in contact allergic dermatitis
Petrosino S, et al.
Allergy, 65(6), 698-711 (2010)
Daria Vinokurova et al.
Frontiers in pharmacology, 9, 698-698 (2018-07-19)
Epipial application is one of the approaches for drug delivery into the cortex. However, passive diffusion of epipially applied drugs through the cortical depth may be slow, and different drug concentrations may be achieved at different rates across the cortical
Natsuo Ueda et al.
Biochimica et biophysica acta, 1801(12), 1274-1285 (2010-08-26)
Ethanolamides of different long-chain fatty acids constitute a class of endogenous lipid molecules generally called N-acylethanolamines (NAEs). They contain N-arachidonoylethanolamine (anandamide), N-palmitoylethanolamine, and N-oleoylethanolamine, which receive considerable attention because of their actions as an endogenous cannabinoid receptor ligand (endocannabinoid), an
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