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870222C

Avanti

18:1 Succinyl PE

Avanti Research™ - A Croda Brand 870222C

Synonym(s):

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl) (sodium salt)

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About This Item

Empirical Formula (Hill Notation):
C45H81NO11PNa
CAS Number:
111613-33-3
Molecular Weight:
866.09
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 2.5 mL (870222C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870222C

concentration

10 mg/mL (870222C-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCN([H])C(CCC(O)=O)=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI

1S/C45H82NO11P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-44(50)54-39-41(40-56-58(52,53)55-38-37-46-42(47)35-36-43(48)49)57-45(51)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,41H,3-16,21-40H2,1-2H3,(H,46,47)(H,48,49)(H,52,53);/q;+1/p-1/b19-17-,20-18-;/t41-;/m1./s1

InChI key

KKEGOYIHHIJUOK-NFCDTPQPSA-M

General description

18:1 Succinyl PE or 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl) (N-succinyl DPPE), belongs to the family of head group modified functionalized lipids. Functionalized lipids mainly act as reporter molecules. N-succinyl DPPE in conjugation with poly(vinyl pyrrolidone) is used in preparation of new drug delivery systems.

Packaging

5 mL Clear Glass Sealed Ampule (870222C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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Poly (vinyl pyrrolidone) conjugated lipid system for the hydrophobic drug delivery
Lee HY, et al.
Macromolecular Research, 15(6), 547-552 (2007)
Mariusz Kepczynski et al.
Biochimica et biophysica acta, 1858(10), 2362-2379 (2016-03-08)
Synthetic lipids and surfactants that do not exist in biological systems have been used for the last few decades in both basic and applied science. The most notable applications for synthetic lipids and surfactants are drug delivery, gene transfection, as

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