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870205C

Avanti

16:0 PDP PE

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio)propionate] (sodium salt), chloroform

Synonym(s):

Sodium (2R)-2,3-bis(hexadecanoyloxy)propyl 2-{3-[(pyridin-2-yl)disulfanyl]propanamido}ethyl phosphate

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About This Item

Empirical Formula (Hill Notation):
C45H80N2O9PNaS2
CAS Number:
474944-16-6
Molecular Weight:
911.22
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 2.5 mL (870205C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870205C

concentration

10 mg/mL (870205C-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(CCSSC1=CC=CC=N1)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C45H81N2O9PS2.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-32-44(49)53-39-41(56-45(50)33-28-26-24-22-20-18-16-14-12-10-8-6-4-2)40-55-57(51,52)54-37-36-46-42(48)34-38-58-59-43-31-29-30-35-47-43;/h29-31,35,41H,3-28,32-34,36-40H2,1-2H3,(H,46,48)(H,51,52);/q;+1/p-1/t41-;/m1./s1

InChI key

IUSHQKJFHVODPF-QUEDAWNRSA-M

General description

16:0 PDP PE, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio) propionate, is a head group modified functionalized lipid. Functionalized lipids mainly act as reporting molecules.[1]

Application

16:0 PDP PE has been used as an inner lipid to synthesizehigh density lipoprotein-like nanoparticles (HDL-like NPs).[2]
16:0 PDP PE has been used to synthesize high-density lipoprotein (HDL)-like nano particles.[2]

Packaging

5 mL Clear Glass Sealed Ampule (870205C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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Synthetic high-density lipoprotein-like nanoparticles potently inhibit cell signaling and production of inflammatory mediators induced by lipopolysaccharide binding Toll-like receptor 4
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Foit L and Thaxton CS
Biomaterials, 100, 67-75 (2016)
Functionalized lipids and surfactants for specific applications
Kepczynski M and Rog T
Biochimica et Biophysica Acta - Biomembranes, 1858(10), 2362-2379 (2016)
Nicholas L Angeloni et al.
Scientific reports, 6, 22915-22915 (2016-03-12)
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