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870125C

Avanti

16:0 Caproylamine PE

Avanti Research™ - A Croda Brand 870125C

Synonym(s):

1,2-Dipalmitoyl-sn-Glycero-3-Phosphoethanolamine-N-(hexanoylamine)

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About This Item

Empirical Formula (Hill Notation):
C43H85N2O9P
CAS Number:
115288-21-6
Molecular Weight:
805.12
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 2.5 mL (870125C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870125C

concentration

10 mg/mL (870125C-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCN([H])C(CCCCC[NH3+])=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O

InChI

1S/C43H85N2O9P/c1-3-5-7-9-11-13-15-17-19-21-23-25-29-33-42(47)51-38-40(39-53-55(49,50)52-37-36-45-41(46)32-28-27-31-35-44)54-43(48)34-30-26-24-22-20-18-16-14-12-10-8-6-4-2/h40H,3-39,44H2,1-2H3,(H,45,46)(H,49,50)/t40-/m1/s1

InChI key

IVLBQYFFAUWDCA-RRHRGVEJSA-N

General description

16:0 Caproylamine PE belongs to the class of head group modified functionalized lipids, which are commonly used as reporting molecules.[1] Caproylamine is a lipid with free amino group on the lipid head. This free amino group enables 16:0 caproylamine PE to interact with biomolecules that are important for drug delivery or target tissue specificity.[2]

Application

16:0 Caproylamine PE may be used to synthesize dibenzyl cyclootyne (DBCO)-oligo(ethylene glycol)-lipid (φ-OEG-lipid) conjugate for generating supported lipid bilayer microarray.[3]

Packaging

5 mL Clear Glass Sealed Ampule (870125C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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Lei Shen et al.
ACS chemical biology, 9(8), 1877-1884 (2014-06-21)
The binding of lectins to glycan receptors on the host cell surface is a key step contributing to the virulence and species specificity of most viruses. This is exemplified by the viral protein hemagglutinin (HA) of the influenza A virus
Luís F Neves et al.
Journal of microencapsulation, 33(4), 391-399 (2016-08-18)
Drug delivery to corneal epithelial cells is challenging due to the intrinsic mechanisms that protect the eye. Here, we report a novel liposomal formulation to encapsulate and deliver a short sequence peptide into human corneal epithelial cells (hTCEpi). Using a
Mariusz Kepczynski et al.
Biochimica et biophysica acta, 1858(10), 2362-2379 (2016-03-08)
Synthetic lipids and surfactants that do not exist in biological systems have been used for the last few decades in both basic and applied science. The most notable applications for synthetic lipids and surfactants are drug delivery, gene transfection, as
Lucas H Hofmeister et al.
ACS nano, 9(4), 4435-4446 (2015-03-15)
In regions of the circulation where vessels are straight and unbranched, blood flow is laminar and unidirectional. In contrast, at sites of curvature, branch points, and regions distal to stenoses, blood flow becomes disturbed. Atherosclerosis preferentially develops in these regions

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