870013C

16:0 MPB PE

Avanti Research^™ - A Croda Brand 870013C

• Synonym(s): 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidophenyl)butyramide] (sodium salt)
• Empirical Formula (Hill Notation): C₅₁H₈₄N₂O₁₁PNa
• CAS Number: 384835-50-1
• Molecular Weight: 955.18
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: liquid
• packaging: pkg of 1 × 2.5 mL (870013C-25mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 870013C
• concentration: 10 mg/mL (870013C-25mg)
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(OCCNC(CCCC(C=C1)=CC=C1N(C(C=C2)=O)C2=O)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
• InChI: 1S/C51H85N2O11P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-32-50(57)61-42-46(64-51(58)33-28-26-24-22-20-18-16-14-12-10-8-6-4-2)43-63-65(59,60)62-41-40-52-47(54)31-29-30-44-34-36-45(37-35-44)53-48(55)38-39-49(53)56;/h34-39,46H,3-33,40-43H2,1-2H3,(H,52,54)(H,59,60);/q;+1/p-1/t46-;/m1./s1
• InChI key: REKODAHLWDSEBQ-FYQWNKFKSA-M

Description

General description

Maleimidophenyl butyramide (MPB) phosphoethanolamine (PE) also known as, DPPE-maleimide contains maleimide, which is a thiol-reactive moiety and a good electrophile. MPB PE is implicated in liposome preparation.[1]

Application

16:0 MPB PE has been used:

• for covalent coupling of monoclonal antibody[2]
• in the lipidation of C-terminal cysteine thiol of ligand binding site-1 (LBS-1)[3]
• to conjugate with peptides for incorporation into liposomes, which were then used in the surface plasmon resonance (SPR)-based binding experiments[4]

16:0 maleimidophenyl butyramide (MPB) phosphoethanolamine (PE) is suitable for use in preparation of liposomes by the film hydration technique.[5]

Packaging

5 mL Clear Glass Sealed Ampule (870013C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372
• pcodes: P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: does not flash
• flash_point_c: does not flash