860529P
Avanti
C12 Sphingosyl PE (d17:1/12:0)
Avanti Research™ - A Croda Brand 860529P, powder
Synonym(s):
N-lauroyl-D-erythro-sphingosyl phosphoethanolamine (C17 base)
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About This Item
Empirical Formula (Hill Notation):
C31H63N2O6P
CAS Number:
Molecular Weight:
590.82
UNSPSC Code:
12352211
NACRES:
NA.25
form
powder
packaging
pkg of 1 × 5 mg (860529P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860529P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
CCCCCCCCCCCC/C=C/[C@@]([H])(O)[C@@]([H])(NC(CCCCCCCCCCC)=O)COP([O-])(OCC[NH3+])=O
General description
C12 Sphingosyl PE (d17:1/12:0) or N-lauroyl-D-erythro-sphingosyl phosphoethanolamine (C17 base) is a synthetic phosphosphingolipid. Sphingosyl phosphoethanolamine (PE) is a derivative of sphingosine, wherein C-2 amine and C-1 hydroxyl groups of sphingosine backbone are substituted with lauric acid and PE groups, respectively.
Application
C12 Sphingosyl PE (d17:1/12:0) or N-lauroyl-D-erythro-sphingosyl phosphoethanolamine (C17 base) may be used:
- as a lipid internal standard for Folch lipid extraction
- as an internal standard for the extraction of lipids using Bligh and Dyer method
- used as a standard to quantify ceramide phosphoethanolamine (CerPE) lipids present in Bacteroides thetaiotaomicron
Packaging
5 mL Amber Glass Screw Cap Vial (860529P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
Certificates of Analysis (COA)
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Ion Mobility-Mass Spectrometry (2019)
Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis.
Eric M Brown et al.
Cell host & microbe, 25(5), 668-680 (2019-05-10)
Sphingolipids are structural membrane components and important eukaryotic signaling molecules. Sphingolipids regulate inflammation and immunity and were recently identified as the most differentially abundant metabolite in stool from inflammatory bowel disease (IBD) patients. Commensal bacteria from the Bacteroidetes phylum also
Hema Balakrishna Bhat et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(9), 3920-3934 (2015-06-11)
Ceramide phosphoethanolamine (CPE), a sphingomyelin analog, is a major sphingolipid in invertebrates and parasites, whereas only trace amounts are present in mammalian cells. In this study, mushroom-derived proteins of the aegerolysin family—pleurotolysin A2 (PlyA2; K(D) = 12 nM), ostreolysin (Oly;
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