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857381P

Avanti

SLM6031434

Avanti Research™ - A Croda Brand (857381P), powder

Synonym(s):

(R)-2-(3-(4-(octyloxy)-3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)pyrrolidine-1-carboximidamide

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About This Item

Empirical Formula (Hill Notation):
C22H30F3N5O2
CAS Number:
1897379-33-7
Molecular Weight:
453.50
UNSPSC Code:
12352211
NACRES:
NA.25

assay

99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (857381P-25mg)
pkg of 1 × 5 mg (857381P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand (857381P)

shipped in

dry ice

storage temp.

−20°C

General description

SLM6031434 is an inhibitor of sphingosine kinase type 2 (SphK2). It consists of pedant 1-guanidino-2-phenyloxadiazolylpyrrolidine group.

Biochem/physiol Actions

SLM6031434 increases the blood sphingosine 1-phosphate (S1P) levels in mice and this occurs due to the inhibition of sphingosine kinase type 2 (SphK2).

Packaging

5 mL Amber Glass Screw Cap Vial (857381P-25mg)
5 mL Amber Glass Screw Cap Vial (857381P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Photoacoustic microscopy reveals the hemodynamic basis of sphingosine 1-phosphate-induced neuroprotection against ischemic stroke
Cao R, et al.
Theranostics, 8(22), 6111-6111 (2018)
Saccharomyces cerevisiae as a platform for assessing sphingolipid lipid kinase inhibitors
Kharel Y, et al.
Testing, 13(4), 6111-6111 (2018)
Sphingosine kinase 2 inhibition and blood sphingosine 1-phosphate levels
Kharel Y, et al.
Journal of Pharmacology and Experimental Therapeutics, 355(1), 23-31 (2015)

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