Skip to Content
MilliporeSigma
All Photos(2)

Key Documents

View All Documentation

857345P

Avanti

VPC 01091

Avanti Research™ - A Croda Brand 857345P, powder

Synonym(s):

((1R,3S)-1-amino-3-(3-octylphenyl)cyclopentyl)methanol (hydrochloride salt)

Sign Into View Organizational & Contract Pricing

Select a Size

All Photos(2)

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C20H34ClNO
CAS Number:
2260669-84-7
Molecular Weight:
339.94
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (857345P-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 857345P

lipid type

phospholipids
bioactive lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

N[C@](C1)(CO)CC[C@@H]1C2=CC=C(CCCCCCCC)C=C2

General description

This product is covered by Patent Number US 7,754,703. Avanti manufactures this under license from University of Virginia.
VPC 01091 is a sphingosine analog.[1]

Biochem/physiol Actions

VPC 01091 is a selective sphingosine 1-phosphate receptor-1 (S1PR1) agonist and sphingosine 1-phosphate receptor-3 (S1PR3) antagonist. It confers protection against lung injury and dysfunction after ischemia-reperfusion (IR) in mice.[1]

Packaging

5 mL Amber Glass Screw Cap Vial (857345P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Matthew L Stone et al.
American journal of physiology. Lung cellular and molecular physiology, 308(12), L1245-L1252 (2015-04-26)
Outcomes for lung transplantation are the worst of any solid organ, and ischemia-reperfusion injury (IRI) limits both short- and long-term outcomes. Presently no therapeutic agents are available to prevent IRI. Sphingosine 1-phosphate (S1P) modulates immune function through binding to a
Byoungjae Kong et al.
Nature communications, 10(1), 185-185 (2019-01-16)
Membrane-disrupting agents that selectively target virus versus host membranes could potentially inhibit a broad-spectrum of enveloped viruses, but currently such antivirals are lacking. Here, we develop a nanodisc incorporated with a decoy virus receptor that inhibits virus infection. Mechanistically, nanodiscs

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service