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855275C

Avanti

08:0 Lyso PC

1-octanoyl-2-hydroxy-sn-glycero-3-phosphocholine, chloroform

Synonym(s):

1-octanoyl-sn-glycero-3-phosphocholine; PC(8:0/0:0)

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About This Item

Empirical Formula (Hill Notation):
C16H34NO7P
CAS Number:
45287-18-1
Molecular Weight:
383.42
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (855275C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 855275C

concentration

10 mg/mL (855275C-25mg)

shipped in

dry ice

storage temp.

−20°C

application

08:0 Lyso PC may be used as a substrate for sphingomyelinase D-like protein (SicTox)in 31P nuclear magnetic resonance (31P NMR) assays.[1][2] It may also be used to study the self-aggregation properties of lysophosphatidylcholines (lysoPC′s).[3]

Packaging

5 mL Clear Glass Sealed Ampule (855275C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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Phospholipase D toxins of brown spider venom convert lysophosphatidylcholine and sphingomyelin to cyclic phosphates
Lajoie DM, et al.
PLoS ONE, 8(8) (2013)
Microstructural characterization of lysophosphatidylcholine micellar aggregates: the structural basis for their use as biomembrane mimics
Vitiello G, et al.
Journal of Colloid and Interface Science, 336(2), 827-833 (2009)
Variable substrate preference among phospholipase D toxins from Sicariid spiders
Lajoie DM, et al.
Test, 290(17), 10994-11007 (2015)
Phospholipase D toxins of brown spider venom convert lysophosphatidylcholine and sphingomyelin to cyclic phosphates
Lajoie DM, et al.
Testing, 8(8) (2013)
R E Stafford et al.
Biochemistry, 28(12), 5113-5120 (1989-06-13)
The critical micelle concentration (cmc) of several lysophospholipids and of a lysophospholipid analogue was determined from surface tension measurements using the maximum bubble pressure method and/or 31P NMR. The use of the maximum bubble pressure method has now been extended

Articles

Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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