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850511P

Avanti

n-octyl-β-D-glucoside

Avanti Research™ - A Croda Brand

Synonym(s):

octyl glucoside; OG; OGP

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About This Item

Empirical Formula (Hill Notation):
C14H28O6
CAS Number:
29836-26-8
Molecular Weight:
292.37
MDL number:
MFCD00063288
UNSPSC Code:
12161902
NACRES:
NA.25

description

n-octyl-β-D-glucopyranoside

assay

>99% (contains <0.2% alpha isomer, TLC)

form

powder

mol wt

292.37 g/mol

packaging

pkg of 1 × 1 g (850511P-1g)
pkg of 1 × 5 g (850511P-5g)

manufacturer/tradename

Avanti Research™ - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@@H](OCCCCCCCC)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1

InChI key

HEGSGKPQLMEBJL-RKQHYHRCSA-N

General description

n-octyl-β-D-glucoside (βOG) is a non-ionic detergent.[1] It has a eight carbon hydrophobic tail.[2]
Octyl glucoside is a dialyzable nonionic detergent for functional solubilization and purification of membrane proteins.

Application

n-octyl-β-D-glucoside is suitable for use to study its self-diffusion coefficients in α-cyclodextrin and β-cyclodextrin solutions at 25°C. [3]

Biochem/physiol Actions

n-octyl-β-D-glucoside (βOG) helps to extract, solubilize and denature membrane proteins. Octyl glucoside has versatile uses including: reconstituting an ion channel, solubilizing an enzyme and incorporating a protein into liposomes. Also, nonionizing detergent complexes are used in protein crystallization studies. It is mainly used in the expression and purification of recombinant protein.[2]

Packaging

20 mL Clear Glass Screw Cap Vial (850511P-1g)
30 mL Amber Wide Mouth Glass Bottle with Screw Cap (850511P-5g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Interactions between n-octyl and n-nonyl beta-D-glucosides and alpha-and beta-cyclodextrins as seen by self-diffusion NMR
Valente AJM, et al.
Journal of Colloid and Interface Science, 281(1), 218-224 (2005)
A single beta-octyl glucoside molecule induces HIV-1 Nef dimer formation in the absence of partner protein binding
Wu M, et al.
Testing, 13(2), e0192512-e0192512 (2018)
APOBEC3G is incorporated into virus-like particles by a direct interaction with HIV-1 Gag nucleocapsid protein
Alce TM and Popik W
The Journal of Biological Chemistry, 279(33), 34083-34086 (2004)

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