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850370C

Avanti

21:0 PC

1,2-diheneicosanoyl-sn-glycero-3-phosphocholine, chloroform

Synonym(s):

PC(21:0/21:0)

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About This Item

Empirical Formula (Hill Notation):
C50H100NO8P
CAS Number:
253685-28-8
Molecular Weight:
874.30
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850370C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850370C

concentration

10 mg/mL (850370C-25mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylcholine is a phospholipid which has a positively charged quaternary amine and a negatively charged phosphate in its headgroup. It can form strong bilayer and component of mammalian membranes.[1]
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

21:0 PC may be used as an internal standard for the quantification of phospholipids (PLs).[2] It may also be used as a phospholipid standard for the analysis of dried lipid extracts of S. meliloti in the positive-ionization mode.[3]

Packaging

5 mL Clear Glass Sealed Ampule (850370C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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Libia Saborido Basconcillo et al.
Journal of lipid research, 50(6), 1120-1132 (2008-12-20)
A shotgun lipidomics approach that allowed the analysis of eight lipid classes directly from crude extracts of the soil bacterium Sinorhizobium meliloti is presented. New MS-MS transitions are reported for the analysis of monomethylphosphatidylethanolamines, dimethylphosphatidylethanolamines, and three bacterial non-phosphorus-containing lipid
Lipid-Protein Interactions in Membranes
The Membranes of Cells, 291-334 (2016)
Alena Janovská et al.
American journal of physiology. Endocrinology and metabolism, 298(4), E779-E786 (2010-01-21)
A high-saturated-fat diet (HFD) induces obesity and insulin resistance (IR). IR has been linked to alterations and increased saturation in the phospholipid composition of skeletal muscles. We aimed to determine whether HFD feeding affects fatty acid (FA) membrane profile in
Frauke Mücksch et al.
Scientific reports, 9(1), 17661-17661 (2019-11-30)
Human immunodeficiency virus type 1 (HIV-1) acquires its lipid envelope during budding from the plasma membrane of the host cell. Various studies indicated that HIV-1 membranes differ from producer cell plasma membranes, suggesting budding from specialized membrane microdomains. The phosphoinositide
Mathias Haag et al.
Metabolites, 2(1), 57-76 (2012-01-01)
Lipids, such as phosphoinositides (PIPs) and diacylglycerol (DAG), are important signaling intermediates involved in cellular processes such as T cell receptor (TCR)-mediated signal transduction. Here we report identification and quantification of PIP, PIP2 and DAG from crude lipid extracts. Capitalizing

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