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850359C

Avanti

16:1 (Δ9-Trans) PC

1,2-dipalmitelaidoyl-sn-glycero-3-phosphocholine, chloroform

Synonym(s):

1,2-di-(9E-hexadecenoyl)-sn-glycero-3-phosphocholine; PC(16:1(9E)/16:1(9E))

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About This Item

Empirical Formula (Hill Notation):
C40H76NO8P
CAS Number:
56816-00-3
Molecular Weight:
730.01
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850359C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850359C

concentration

10 mg/mL (850359C-25mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes.[1] It is also an important component of the mucosal layer of the colon.[2]
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

16:1 (Δ9-Trans) PC is suitable for use to investigate its role in cell proliferation.[3] It is also suitable for use as a neutral or helper lipid to study the interplay of liposomal composition, physicochemical characteristics and fusion capacity.[4]

Biochem/physiol Actions

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance.[2] It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.[5]

Packaging

5 mL Clear Glass Sealed Ampule (850359C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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Integrative Medicine - E-Book (2017)
Deciphering the Functional Composition of Fusogenic Liposomes
Kolavsinac R, et al.
International Journal of Molecular Sciences, 19(2), 346-346 (2018)
The Membranes of Cells (2016)
Interference of phosphatidylcholines with in vitro cell proliferation?no flock without black sheep
Werlein A, et al.
Biochimica et Biophysica Acta - Biomembranes, 1848(7), 1599-1608 (2015)
Efficacy of injections of phosphatidylcholine into fat deposits-a non-surgical alternative to liposuction in body-contouring
Karl GH, et al.
Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India, 38(2), 119-119 (2005)

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