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840036C

Avanti

10:0 PS

1,2-didecanoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform

Synonym(s):

PS(10:0/10:0)

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About This Item

Empirical Formula (Hill Notation):
C26H49NO10PNa
CAS Number:
321863-22-3
Molecular Weight:
589.63
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (840036C-10mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 840036C

concentration

10 mg/mL (840036C-10mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O.[Na+]

InChI

1S/C26H50NO10P.Na/c1-3-5-7-9-11-13-15-17-24(28)34-19-22(20-35-38(32,33)36-21-23(27)26(30)31)37-25(29)18-16-14-12-10-8-6-4-2;/h22-23H,3-21,27H2,1-2H3,(H,30,31)(H,32,33);/q;+1/p-1/t22-,23+;/m1./s1

InChI key

MNHRZRUSKRPBDA-RFPXDPOKSA-M

General description

Glycerophosphoserines (PS) interacts with spectrin and maintains red blood cell (RBC) membrane asymmetry.[1]

Application

1,2-didecanoyl-sn-glycero-3-phospho-L-serine has been used for the preparation of sucrose-loaded liposomes.[2]

Packaging

5 mL Clear Glass Sealed Ampule (840036C-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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Binding of PLD2-generated phosphatidic acid to KIF5B promotes MT1-MMP surface trafficking and lung metastasis of mouse breast cancer cells
Wang Z, et al.
Developmental Cell, 43(2), 186-197 (2017)
Phospholipidomics reveals differences in glycerophosphoserine profiles of hypothermically stored red blood cells and microvesicles
Bicalho B, et al.
Biochimica et Biophysica Acta - Biomembranes, 1828(2), 317-326 (2013)
Emily R Schenk et al.
Journal of mass spectrometry : JMS, 50(1), 88-94 (2015-01-21)
Bacterial resistance to antibiotics has become an increasing threat, requiring not only the development of new targets in drug discovery, but more importantly, a better understanding of cellular response. In the current study, three closely related Escherichia coli strains, a
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly

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