840033P

14:0 PS

Avanti Research^™ - A Croda Brand

• Synonym(s): 1,2-ditetradecanoyl-sn-glycero-3-phospho-L-serine (sodium salt); DMPS; PS(14:0/14:0)
• Empirical Formula (Hill Notation): C₃₄H₆₅NO₁₀PNa
• CAS Number: 105405-50-3
• Molecular Weight: 701.84
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• description: 1,2-dimyristoyl-sn-glycero-3-phospho-L-serine (sodium salt)
• assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 10 mg (840033P-10mg); pkg of 1 × 200 mg (840033P-200mg); pkg of 1 × 25 mg (840033P-25mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• lipid type: phospholipids; cardiolipins
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[Na+]
• InChI: 1S/C34H66NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-32(36)42-27-30(28-43-46(40,41)44-29-31(35)34(38)39)45-33(37)26-24-22-20-18-16-14-12-10-8-6-4-2;/h30-31H,3-29,35H2,1-2H3,(H,38,39)(H,40,41);/q;+1/p-1/t30-,31+;/m1./s1
• InChI key: QSHQBWBFNCFHLO-MFABWLECSA-M

Description

General description

Phosphatidylserine (PS) is a retinal phospholipid, which carries long-chain highly unsaturated fatty acyl groups.

Application

14:0 PS may be used as an internal standard for spiking serum lipid samples for liquid chromatography-mass spectroscopy analysis and as a component in the phospholipid monolayer to mimic model cancer cell membrane for the anticancer drug doxorubicin (DOx) interaction studies. It has been used in lipid binding assay to assess the binding of monoclonal antibodies (mAbs).

Biochem/physiol Actions

Phosphatidylserine (PS) helps to activate protein kinase C (PKC). It may possess anti-inflammatory properties. PS is also known to participate in tyrosine hydroxylase activation. It is also involved in the uptake of Ca2+ and glucose.

Packaging

5 mL Amber Glass Screw Cap Vial (840033P-10mg)

5 mL Amber Glass Screw Cap Vial (840033P-200mg)

5 mL Amber Glass Screw Cap Vial (840033P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable