840009C

PAF (from Heart PC)

Avanti Research^™ - A Croda Brand 840009C

• Synonym(s): 1-alkyl-2-acetoyl-sn-glycero-3-phosphocholine
• CAS Number: 65154-06-5
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 1 mL (840009C-5mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 840009C
• concentration: 5 mg/mL (840009C-5mg)
• lipid type: lipid extracts; phosphoglycerides
• shipped in: dry ice
• storage temp.: −20°C
• InChI: 1S/C12H26NO7P/c1-6-17-9-12(20-11(2)14)10-19-21(15,16)18-8-7-13(3,4)5/h12H,6-10H2,1-5H3/t12-/m1/s1
• InChI key: OLGKYSVSAKLUHK-GFCCVEGCSA-N

Description

General description

Platelet-activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine), an endogenous phospholipid is synthesized by several cells.[1] PAF is a phosphatidylcholine derivative.[2]

Biochem/physiol Actions

Platelet-activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is linked with arterial thrombosis, endotoxic shock, acute inflammation and acute allergic disease. It acts as a mediator of pathogenesis of ulcerative colitis and Crohn′s disease in human colon.[1] It also participates in platelet activation and inflammation.[2]

Packaging

5 mL Clear Glass Sealed Ampule (840009C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372
• pcodes: P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: does not flash
• flash_point_c: does not flash