810263P
Avanti
C11 TopFluor™ Dihydroceramide
N-[11-(dipyrrometheneboron difluoride)undecanoyl]-D-erythro-sphinganine, powder
Synonym(s):
N-[11-(TopFluor)undecanoyl]-D-erythro-sphinganine
Sign Into View Organizational & Contract Pricing
All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C42H72N3O3F2
CAS Number:
Molecular Weight:
705.04
UNSPSC Code:
12352211
Recommended Products
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 250 μg (810263P-250ug)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810263P
shipped in
dry ice
Storage temp.
−20°C
General description
There are two types of dihydroceramide desaturases, such as DES1 and DES2. DES1 is ubiquitously present and DES2 is present in the gut and skin.
Biochem/physiol Actions
Dihydroceramide (DH-Cer) plays a key role in de novo biosynthesis of sphingolipid by acting as an intermediate. Dihydroceramide modulates autophagy. This metabolite can stimulate fibrosis in hepatic steatosis model. It can enhance the lipid droplets by damaging the autophagic flux.
Packaging
5 mL Amber Glass Screw Cap Vial (810263P-250ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.
If you need assistance, please contact Customer Support
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Dihydroceramide Biology STRUCTURE-SPECIFIC METABOLISM AND INTRACELLULAR LOCALIZATION
Kok JW, et al.
The Journal of Biological Chemistry, 272(34), 21128-21136 (1997)
Dihydroceramides: from bit players to lead actors
Siddique M M, et al.
Test, 290(25), 15371-15379 (2015)
Dihydroceramide is a key metabolite that regulates autophagy and promotes fibrosis in hepatic steatosis model
Lee Ah young, et al.
Biochemical and biophysical research communications, 494(3-4), 460-469 (2017)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service