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810163C

Avanti

16:0-06:0 NBD PG

Avanti Research™ - A Croda Brand 810163C

Synonym(s):

1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-[phospho-rac-(1-glycerol)] (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C34H60N5O13P
CAS Number:
474942-85-3
Molecular Weight:
777.84
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810163C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810163C

concentration

1 mg/mL (810163C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) phosphatidylglycerol (PG) is a fluorescently labeled lipid where the NBD moiety is attached to the phosphatidylglycerol (PG) lipid. Phosphatidylglycerol (PG) is abundant in the pulmonary surfactant. It is localized to the alveoli.

Application

16:0-06:0 NBD PG is suitable for lipoteichoic acid synthase (eLtaS) enzyme assay.

Biochem/physiol Actions

7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) labeled fluorescence probes efficiently contributes to study the formation membranes, micelles and reverse micelles. Phosphatidylglycerol (PG) plays a vital role in the regulation of innate immune response.
7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) labeled lipids function as potential fluorophores in the study of biological and model membranes. NBD- phosphatidylglycerol (PG) is useful as a substrate in the analysis of enzymatic reactions. PG controls inflammatory mechanism against viral infections.

Packaging

5 mL Amber Glass Screw Cap Vial (810163C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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H Raghuraman et al.
Biochimica et biophysica acta, 1768(5), 1258-1267 (2007-03-17)
Lipids that are labeled with the NBD (7-nitrobenz-2-oxa-1,3-diazol-4-yl) group are widely used as fluorescent analogues of native lipids in biological and model membranes to monitor a variety of processes. The NBD group of acyl chain labeled NBD lipids is known
Marianna Agassandian et al.
Biochimica et biophysica acta, 1831(3), 612-625 (2012-10-03)
Pulmonary surfactant is essential for life and is composed of a complex lipoprotein-like mixture that lines the inner surface of the lung to prevent alveolar collapse at the end of expiration. The molecular composition of surfactant depends on highly integrated
Chi-Jung Weng et al.
Molecular membrane biology, 33(1-2), 23-28 (2016-07-28)
To investigate the effect of fluorescent probe on the properties of membranes, we studied model membranes composed of 1,2- dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and 1-palmitoyl 2-oleoyl-sn-glycero-3-phosphocholine (POPC) in the presence and absence of fluorescent probe. The morphology of giant unilamellar vesicles (GUVs)
Rachel Fickes et al.
Rapid communications in mass spectrometry : RCM, 30(24), 2601-2606 (2016-10-01)
Structural analogs of the bioactive lipid 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol were synthesized with a xylitol polar head group and both diacyl and diether radyl groups. Mass spectral characterization of xylitol phospholipids (PX) was carried out using collisional activation and high-resolution mass measurements of
Maria Mercedes Palomino et al.
Microbiology (Reading, England), 159(Pt 11), 2416-2426 (2013-09-10)
The probiotic Gram-positive bacterium Lactobacillus casei BL23 is naturally confronted with salt-stress habitats. It has been previously reported that growth in high-salt medium, containing 0.8 M NaCl, leads to modifications in the cell envelope of this bacterium. In this study
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