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810151C

Avanti

14:0-06:0 NBD PE

Avanti Research™ - A Croda Brand 810151C

Synonym(s):

1-myristoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoethanolamine

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About This Item

Empirical Formula (Hill Notation):
C31H52N5O11P
CAS Number:
328946-24-3
Molecular Weight:
701.75
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810151C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810151C

concentration

1 mg/mL (810151C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescent probe which contains NBD, a fluorophore, attached to the headgroup of phosphatidylethanolamine mostly present in brain. It Phosphoethanolamine is the second most abundant, metabolically related aminophospholipid, localized at the membrane interface.

Biochem/physiol Actions

Phosphoethanolamine present in cardiac myocytes helps in preventing cell damage after ischemia. N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) aids is monitoring the Red edge excitation shift (REES) effects with its unique motional and dielectric properties.

Packaging

5 mL Amber Glass Screw Cap Vial (810151C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

Certificates of Analysis (COA)

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Application of NBD-labeled lipids in membrane and cell biology
Fluorescent methods to study biological membranes, 37-50 (2012)
Jean E Vance et al.
Biochimica et biophysica acta, 1831(3), 543-554 (2012-09-11)
Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are metabolically related membrane aminophospholipids. In mammalian cells, PS is required for targeting and function of several intracellular signaling proteins. Moreover, PS is asymmetrically distributed in the plasma membrane. Although PS is highly enriched in
S C Lopes et al.
Biochimica et biophysica acta. Biomembranes, 1861(6), 1152-1161 (2019-03-07)
Mitochondrial membranes are pointed out as the site of cardiotoxic action of local anaesthetics. Its three main phospholipids components are phosphatidylcholine, phosphatidylethanolamine and cardiolipin. Cardiolipins, in eukaryotes, are only found in mitochondria and are essential for the maintenance of its

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