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800605C

Avanti

18:1 Ethylene Glycol

1-2-dioleoyl ethylene glycol, chloroform

Synonym(s):

1,2-di-(9Z-octadecenoyl) ethylene glycol; DEG(18:1(9Z)/18:1(9Z))

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About This Item

Empirical Formula (Hill Notation):
C38H70O4
CAS Number:
928-24-5
Molecular Weight:
590.96
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (800605C-10mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 800605C

concentration

10 mg/mL (800605C-10mg)

lipid type

neutral glycerides
neutral lipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C38H70O4/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-37(39)41-35-36-42-38(40)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20H,3-16,21-36H2,1-2H3/b19-17+,20-18+

InChI key

NKSOSPOXQKNIKJ-XPWSMXQVSA-N

General description

18:1 Ethylene glycol (1-2-dioleoyl ethylene glycol) is a nonpolar lipid. The oleic acid esters are generally synthesized with polyols like ethylene glycol. 18:1 Ethylene glycol consists of two oleic acid esterified to ethylene glycol.

Application

18:1 Ethylene glycol (1-2-dioleoyl ethylene glycol) may be used as a phosphatidic acid synthesis inhibitor in rabbit kidney epithelial cells. It may also be used as an internal standard in normal-phase ultrahigh-performance liquid chromatography-atmospheric pressure chemical ionization mass spectroscopy (NP-UHPLC/APCI-MS) for human plasma lipidomic analysis.

Biochem/physiol Actions

18:1 Ethylene glycol or dioleoyl ethylene glycol (DOEG) is an inhibitor of protein kinase C.

Packaging

5 mL Clear Glass Sealed Ampule (800605C-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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G S Schuster et al.
Dental materials : official publication of the Academy of Dental Materials, 16(4), 297-302 (2000-06-01)
Diacylglycerol-kinase (DAG-kinase) is an enzyme that phosphorylates diacylglycerol (DAG) to phosphatidic acid (PA), which serves as a precursor to phosphoglycerides involved in cell signaling or as cell membrane structural components. DAG-kinase can be inhibited by diacylethylene glycols (DAEG). We hypothesize
Shawn Hopewell et al.
Metabolism: clinical and experimental, 57(12), 1677-1684 (2008-11-18)
Phosphatidylinositol (PI) has been shown to stimulate reverse cholesterol transport in animal models and to increase plasma apolipoprotein (apo) A-I levels and high-density lipoprotein cholesterol in human subjects. The objective of this study was to determine the molecular mechanism through
Asma Chaari et al.
Journal of oleo science, 66(5), 455-461 (2017-04-07)
The production of fatty acid esters from stearic, oleic, and palmitic acids and polyols (ethylene glycol and glycerol) was investigated in this work. A series of montmorillonite-based clays catalysts (KSF, KSF/0, KP10, and K10), having different physicochemical properties, were used
Michal Holčapek et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 990, 52-63 (2015-04-10)
Differences among lipidomic profiles of healthy volunteers, obese people and three groups of cardiovascular disease (CVD) patients are investigated with the goal to differentiate individual groups based on the multivariate data analysis (MDA) of lipidomic data from plasma, erythrocytes and
Michal Holčapek et al.
Journal of chromatography. A, 1377, 85-91 (2014-12-30)
A novel normal-phase (NP) ultrahigh-performance liquid chromatography-mass spectrometry (UHPLC/MS) method is developed for a separation and quantitation of nonpolar lipid classes occurring in human plasma, erythrocytes and plasma lipoprotein fractions. The baseline class separation of cholesteryl esters (CE), cholesterol, triacylglycerols

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