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791645C

Avanti

18:1-d7-cholesterol

Avanti Research™ - A Croda Brand 791645C

Synonym(s):

cholest-5-en-3β-yl oleate-d7

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About This Item

Empirical Formula (Hill Notation):
C45H71 D7O2
CAS Number:
2260669-48-3
Molecular Weight:
658.14
UNSPSC Code:
41141804
NACRES:
NA.25

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (791645C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 791645C

concentration

1 mg/mL (791645C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

Cholesteryl oleate is a cholesteryl ester. 18:1-d7-cholesterol is a deuterated oleic acid cholesteryl ester.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH™ LIPIDOMIX™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Application

18:1-d7-cholesterol may be used in the reconstitution of acetylated low-density lipoprotein (acLDL) liposome for trafficking studies in U2OS-SRA cells.

Biochem/physiol Actions

Elevation in cholesterol ester levels and its accumulation is implicated in prostate cancer (PCa). Cholesteryl oleate, may serve as a potential biomarker for diagnosis of PCa.

Packaging

5 mL Clear Glass Sealed Ampule (791645C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Product No.
Description
Pricing

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk_germany

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Heart Proteomics, 967-1009 (2001)
Jia Li et al.
Scientific reports, 6, 20984-20984 (2016-02-13)
In-depth delineation of lipid metabolism in prostate cancer (PCa) is significant to open new insights into prostate tumorigenesis and progression, and provide potential biomarkers with greater accuracy for improved diagnosis. Here, we performed lipidomics and transcriptomics in paired prostate cancer
McKenna Feltes et al.
Journal of lipid research, 60(3), 707-716 (2019-01-09)
Cholesterol is an essential structural component of cellular membranes and precursor molecule for oxysterol, bile acid, and hormone synthesis. The study of intracellular cholesterol trafficking pathways has been limited in part due to a lack of suitable cholesterol analogues. Herein

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