791225P
Avanti
14:0 PE-DTPA(Cu)
Avanti Research™ - A Croda Brand 791225P, powder
Synonym(s):
1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (copper salt)
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About This Item
Empirical Formula (Hill Notation):
C47H94CuN7O17P
CAS Number:
Molecular Weight:
1123.81
UNSPSC Code:
12352211
NACRES:
NA.25
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (791225P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 791225P
shipped in
dry ice
storage temp.
−20°C
General description
1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid or 14:0 PE-DTPA is a synthetic phosphatidylethanolamine derivative.[1]
Inclusion of copper (Cu2+) ions in bicelles in the form of a lipid chelate resulted in a 10-fold T1 reduction and 2.7-fold increase in S/N of spectra for static experiments. This improvement would allow 2D experiments on membrane proteins in aligned lipid bilayers that typically take 3 days to be completed in <1.5 days. The technique is particularly beneficial to the study of membrane disrupting/permeating systems (such as antimicrobial peptides, toxins, amyloid peptides, and fusion peptides) whose concentration cannot be increased, as they result in nonlamellar conditions.
Application
Packaging
5 mL Amber Glass Screw Cap Vial (791225P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
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Immunity, 31(6), 873-884 (2009)
Kazutoshi Yamamoto et al.
Journal of the American Chemical Society, 132(20), 6929-6931 (2010-05-04)
Recent studies have demonstrated the abilities of solid-state NMR techniques to solve atomic-level-resolution structures and dynamics of membrane-associated proteins and peptides. However, high-throughput applications of solid-state NMR spectroscopy are hampered by long acquisition times due to the low sensitivity of
Direct observation of the three regions in $\alpha$-synuclein that determine its membrane-bound behaviour
Fusco Giuliana, et al.
Nature Communications, 5, 3827-3827 (2014)
Tumor targeting and imaging with dual-peptide conjugated multifunctional liposomal nanoparticles
Rangger C, et al.
International journal of nanomedicine, 8(6), 4659-4659 (2013)
Rupa R Sawant et al.
Pharmaceutical research, 29(2), 375-383 (2011-08-17)
To evaluate and compare anticancer therapeutic effect of palmitoyl ascorbate liposomes (PAL) and free ascorbic acid (AA). Liposomes incorporating palmitoyl ascorbate (PA) were prepared and evaluated for PA content by HPLC. To elucidate mechanism of action of cell death in
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