640007P
Avanti
Girard Reagent
Avanti Research™ - A Croda Brand
Synonym(s):
1-(2-hydrazinyl-2-oxoethyl)pyridin-1-ium bromide
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About This Item
Empirical Formula (Hill Notation):
C7H10BrN3O
Molecular Weight:
232.08
UNSPSC Code:
12352116
NACRES:
NA.28
Recommended Products
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 250 mg (640007P-250mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
Girard Reagents are N-substituted glycine hydrazides. They are classified as Girard-T (trimethylacetylhydrazide ammonium chloride), Girard-P (pyridinioacetohydrazide chloride) and Girard-D (N,N-dimethylglycine hydrazide hydrochloride). Girard hydrazones have a quaternary nitrogen moiety.
Biochem/physiol Actions
Girard reagents facilitate the isolation of carbonyl compounds from their complex mixtures, by generating water-soluble hydrazones. These reagents are sensitive and selective. Girard P reagent is used for the derivatization of oxosteroids to form the corresponding Girard hydrazones, which can be detected by tandem mass spectroscopy or electrospray (ES) mass spectrometry.
Packaging
20 mL Clear Glass Screw Cap Vial (640007P-250mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Analysis of oxysterols by electrospray tandem mass spectrometry
Griffiths WJ, et al.
Journal of the American Society For Mass Spectrometry, 17(3), 341-362 (2006)
Transition metal complexes with Girard reagents and their hydrazones
Vojinovic-Jevsic LS, et al.
J. Serb. Chem. Soc., 77(9), 1129-1155 (2012)
Highly automated nano-LC/MS-based approach for thousand cell-scale quantification of side chain-hydroxylated oxysterols
Roberg-Larsen H, et al.
Journal of Lipid Research, 55(7), 1531-1536 (2014)
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