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W329703

Sigma-Aldrich

L-Leucine

99%, FG

Synonym(s):

(S)-2-Amino-4-methylpentanoic acid

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About This Item

Linear Formula:
(CH3)2CHCH2CH(NH2)CO2H
CAS Number:
61-90-5
Molecular Weight:
131.17
FEMA Number:
3297
Beilstein/REAXYS Number:
1721722
EC Number:
200-522-0
Council of Europe no.:
10482
MDL number:
MFCD00002617
UNSPSC Code:
12164502
PubChem Substance ID:
24901619
Flavis number:
17.012
NACRES:
NA.21

biological source

plant

Quality Level

400

grade

FG
Kosher

agency

meets purity specifications of JECFA

reg. compliance

EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 172.320
FDA 21 CFR 172.804

assay

99%

optical activity

[α]20/D +15.5°, c = 2 in 6 M HCl

mp

>300 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

odorless

SMILES string

CC(C)C[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1

InChI key

ROHFNLRQFUQHCH-YFKPBYRVSA-N

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General description

L-Leucine is a branched-chain amino acid mainly found in whey proteins.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Whey proteins in the regulation of food intake and satiety.
Luhovyy BL, et al.
Journal of the American College of Nutrition, 26(6), 704S-712S (2007)
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T Yoshimasa et al.
The Journal of clinical investigation, 69(3), 643-650 (1982-03-01)
To elucidate the physiological and pathophysiological significance of methionine- and leucine-enkephalin (Met-and Leu-enkephalin, respectively) in human sympathoadrenal system, the contents of these peptides in normal human sympathetic nervous system, adrenal medulla, and pheochromocytomas were determined by specific radioimmunoassays combined with
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Amino acids function as precursors for de novo protein synthesis. In addition, however, they play a key role as nutritional signals that regulate multiple cellular processes. There is ample in vitro and in vivo evidence showing that muscle tissue responds
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Chromatograms

application for HPLC

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